Constipation is always a sign of deficient intestinal flora. Normal gut flora is very involved in normal stool formation and elimination. Healthy evacuation should take place once or twice a day. If this is not the case, action must be taken to restore normal digestion. It is a symptom that many MS patients suffer from.
The Persian physician Ibn Sina Avicenna wrote about the importance of regular enemas in the 11th Century as part of treatment for serious health conditions. They are highly advocated for the treatment of conditions such as autoimmune disease and cancer. This rings true to me, having done several liver flushes involving enemas and colonic irrigation; as a result of the latter and diet changes, constipation is no longer a problem for me.
Persistent constipation is dangerous and it is important to resolve this problem. It leads to all sorts of digestive disorders including bowel cancer and poisons the whole body because of the toxins which remain in it. Many specialists recommend enemas daily, before bed followed by a warm bath with Epsom salt, seaweed powder, cider vinegar, bicarbonate of soda or sea salt. Rubbing cold pressed olive oil into the abdominal area after the bath is said to be a good idea also to relieve constipation, the skin will absorb it well enough. Enemas are an immediate solution but the way to fix constipation long-term is through diet and probiotics.
Laxatives are not recommended for people with digestive problems, even if they are herbal. Following the MS diet will relieve constipation, but it is also important to deal with the cause: gut dysbiosis. If you are constipated, drinking more water throughout the day and eating more vegetables will definitely help.
Another thing you can try is taking an adaptagen.
Drinking a warm cup of water first thing followed by a warm cup of water and lemon can also be helpful for constipation.